Vitamin E Deficiency in the Monkey

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Vitamin E Deficiency in the Monkey . Iv .

NEMIA regularly develops in the rhesus monkey (Macaca mulatta) when it is deprived of vitamin E.1 The anemia is accompanied by granulocytosis,’ an increased concentration of bone marrow deoxyribonucleic acid,2 a reduction in the maximal Cr5’ survival time of the erythrocytes,3 a slightly elevated reticulocyte count1 and a prompt reticulocytosis following vitamin E administration. This combinati...

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Vitamin E Deficiency in the Monkey

Eight young rhesus monkeys were fed a purified diet devoid of vitamin E. After from 6 to 13 months of feeding, all the animals developed signs of vitamin E deficiency. The signs of vitamin E deficiency in the monkey include muscular dystrophy, elevated excretion of creatine, allantoin, and free amino acids and decreased excretion of creatinine. The vitamin E-deficient monkeys all developed anem...

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Nutritional Cytopenia (vitamin M Deficiency) in the Monkey

Young rhesus monkeys (Macaca mulatta) were given a diet containing casein, polished rice, whole wheat, salt mixture, sodium chloride, cod liver oil, and ascorbic acid. They developed a syndrome characterized by anemia, leukopenia, and loss of weight. Ulceration of the gums and diarrhea were common, and death occurred between the 26th and 100th day. 4 monkeys were given the deficient diet supple...

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Abnormalities of lipid metabolism in the vitamin E-deficient monkey.

A soybean protein diet was used to induce vitamin E deficiency in rhesus monkeys. The deficient monkeys had reduced triglyceride concentrations in liver and skeletal muscle, but the cholesterol concentration in their skeletal muscle was increased. A constant amount of radioactively labeled (3)H-cholesterol-7alpha-(3)H was fed daily for 48-114 days to control and vitamin E-deficient monkeys to s...

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Ataxia with Vitamin E Deficiency in Norway

OBJECTIVE Ataxia with vitamin E deficiency (AVED) is a rare autosomal recessive neurological disorder which usually starts in childhood. The clinical presentation is very similar to Friedreich ataxia, most patients have progressive truncal and extremity ataxia, areflexia, positive Babinski sign, dysarthria and sensory neuropathy. METHODS We made an inquiry to our colleagues in Norway, we incl...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1958

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(19)68063-4